Lesson #3 will be based on the B Locus. The B Locus attained it's name from the word Brown.
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Red and White Boston Terriers, also known as Liver and White, have become the most well known of the
non-traditional colors. These Boston Terriers are self colored, having both red pigmented nose/paw
pads/and iris, as well as coat color. There are many varying shades of red and white Boston Terriers, from
brightly colored orange/copper red Boston Terriers to very vivid red and white.
Puppies born of the red coloring have differing colors of eyes. After the "puppy blue" color of the eyes
dissipate, the iris can become various shades of green. It is not normal for the eye to remain this green
coloring. Most all of the time the eyes will change at around 4-6 months and the iris will become a hazel
color, at times even darkening to a rich amber color.
A true red and white Boston Terrier has no black hairs or pigmentation. Though the red Boston Terrier has
a reputation for being named the "seal" Boston Terrier by many unknowledgeable breeders, in actuality
there is no known correlation of true seal to red/brown coloring.
Nose Color: Self Colored Red
Eye Color: Amber, Hazel
Red and White Genetically Known As: b/b ***These Boston Terriers are NOT Seal and White***
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Brown and White Boston Terriers, also known as Chocolate and White, are genetically the same as red
Boston Terriers. They are a much deeper and darker coloring. There are said to be 3 differing mutations of
the b gene in Boston Terriers, bs, bd, bc. The superscripts stand for the following: (s)top, (d)eletion, and
(c)ysteine. The first mutation creates a premature stop codon in the gene. The second has a small
segment of DNA missing from the gene, and the third mutation causes the normal amino acid to be replaced
by different one (cysteine). The three mutations are found in most breeds that are recessive for b/b brown,
and no genetic differences between the various combinations from breed to breed have been found. This
is different from the feline species, as different b mutations correlate to brown and red. Researchers have
yet to pinpoint precisely why in the canine breed there are differing hues of coat color from red to brown as
the mutations do not seem to be the reason in all cases.
Nose Color: Self Colored Brown
Eye Color: Amber, Hazel
Brown and White Genetically Known As: b/b ***These Boston Terriers are NOT Seal and White***
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- Although they are known as "Red" Boston Terriers, their genetic color chromosomes are situated within
the B locus and is known as brown. There is a "true red" or clear red gene on the E locus, however, no
Boston Terrier has yet to DNA color test as a e/e "true red" Boston Terrier. All those tested have only
resulted in b/b.
- Although brown has been defined in some articles and literature as being a "dilute" of black, this
terminology is not entirely correct. A proper way to describe the effects of the B locus in regards to black
is actually a FADING of black to brown. Understanding it this way causes less confusion when considering
the role of the D locus. When those who are not well versed in color genetics read that brown is a
"dilute" of black they tend to assume that ALL brown Boston Terriers must carry the dilute gene and are
then able to produce dilute colorings which is NOT the case.
- There has yet to be a litter produced from two b/b Boston Terriers of true lineage, purebred, and DNA
verified parentage that has resulted in any puppies with dominant coloring of black/brindle/seal, or
any puppy with a nose that is not self colored or self colored dilute no matter the recessive genes they
may carry.
***Important Facts To Note About Red/Brown Boston Terriers***
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